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The AM.NUS team comprising of Dr Cai Yanli, Chang Soon Yee, Gan Soo Wah, Dr Ma Sha, A/Prof Lu Wen Feng and A/Prof Yen Ching-Chiuan has published a review paper titled “Nanocomposite bioinks for 3D bioprinting”. This paper explores the recent developments of cell-laden nanocomposite bioinks for 3D bioprinting and cell-materials interactions. 3D bioprinting is an advanced technology to fabricate artificial 3D tissue constructs containing cells and hydrogels for tissue engineering and regenerative medicine. 

This review paper emphasizes the recent developments of cell-laden nanocomposite bioinks for 3D bioprinting, focusing on:

1. Their reinforcement effects and mechanisms, including viscosity, shear-thinning property, printability, mechanical properties, structural integrity, and biocompatibility.
2. Cell-material interactions and the underlying mechanisms between the cells and the nanomaterials.
3. Summary of biomedical applications of cell-laden nanocomposite bioinks with a focus on bone and cartilage tissue engineering.
4. Limitations and challenges of current cell-laden nanocomposite bioinks.
5. Prospects of designing multi-component bioinks with multi-functionality for various biomedical applications.

 

Read the paper here.

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